CYTPOWER: IMPLEMENTATION OF CYTOTOXIC POWER CONCEPT IN PYTHON

Main Article Content

Maksim Aleksandrovich Terpilovskii, Dr.
Nikolay Vasilievich Goncharov, Dr.

Abstract

Currently existing methods and parameters are inadequate for representative and quanititative assessment of cytotoxic activity of chemical compounds. Recently, we have introduced a concept of cytotoxic power which provides an effective way to a reasonable estimation and comparative analysis of cytotoxic activity of chemical agents. The basis of this concept is an integrative parameter that relies on important toxicological principles: dose of compound related to a cell number and exposure-time-response relationship of its activity.


Herein, we propose a proof-of-concept implementation of our concept of cytotoxic power as a package developed in Python programming language. The package is free and available on GitHub repository.

Article Details

How to Cite
TERPILOVSKII, Maksim Aleksandrovich; GONCHAROV, Nikolay Vasilievich. CYTPOWER: IMPLEMENTATION OF CYTOTOXIC POWER CONCEPT IN PYTHON. Journal of Bioinformatics and Genomics, [S.l.], n. 4 (9), nov. 2018. ISSN 2530-1381. Available at: <http://journal-biogen.org/article/view/105>. Date accessed: 12 dec. 2018. doi: http://dx.doi.org/10.18454/jbg.2018.4.9.1.
Section
Novel computational tools and databases
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