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Интеграция генетических факторов риска и лекарственно-ассоциированных генов при терапии биполярного расстройства: биоинформатический и системно-фармакологический анализ сигнальных путей
Exact gene overlap between the strict BD mapping set and quantitative Tier 1 targets
the raw curated sets contained 80 and 22 symbols, respectively, with HTR6 as the only shared gene; the illustrative protein-coding analysis used 63 and 22 genes and an HGNC universe of 19,296 genes (p = 0.0695); circle areas are schematic; the diagram does not establish a therapeutic mechanism or treatment-response biomarker; source data are provided in Supplementary Table S24