bars show reported ranges and circles single reported values on a logarithmic scale; the shaded band marks the manufacturer's 5- to 10-fold claim; the two entries for Martin et al. [3] derive from the same dataset and illustrate the difference between raw (coverage-based) and yield-adjusted enrichment defined in Section 2.2; the range shown for conventional amplicon and capture methods is indicative only (Section 3.2.3); values are taken from the sources cited in Sections 3.2.3, 3.3 and 3.4; bracketed numbers refer to the reference list